For UK healthcare professionals
ChondroFiller® liquid: product, technique and evidence for UK healthcare professionals.
A cell-free, two-component type I collagen matrix, as described in the published literature, supplied as a collagen solution and a neutralising solution that are mixed through an adapter at the point of use and form a stable gel in the prepared defect within minutes.

At a glance
Composition, presentation and regulatory status.
- Composition
- Type I collagen matrix; cell-free, two-component1
- Presentation
- Dual-chamber syringe: collagen and neutralising solutions, mixed through an adapter at the point of use2
- Formats
- 1.0 ml, 1.5 ml, 2.3 ml2
- Setting time
- Approximately 3 to 5 minutes2
- Regulatory status
- Listed on the MHRA register of medical devices. Registration is not approval.
- Collagen concentration
- 8 mg per ml, type I, in buffer3
In this section
Product, techniques, rehabilitation, evidence and resources.
Product information
Composition, indications, contraindications, handling and storage.
OpenTechniques
Ultrasound-guided injection and the nine-step surgical technique, with outcome data.
OpenRehabilitation
Phased load, mobilisation and activity tables for femoral, patellofemoral, talar and hip defects.
OpenEvidence
Published references and manufacturer documents, with study design and follow-up.
OpenResources
Every document with a cover and a direct link, the hosted papers and the animation.
OpenProfessional FAQ
Short, sourced answers to what clinics ask before a first case.
Open
Techniques
Injected as a liquid, set in minutes.
The ultrasound-guided injection the manufacturer describes for the thumb base, with its outcome data, and the surgical technique guide condensed into nine sourced steps.
References
- 1.Perez-Carro L, Mendoza Alejo PR, Gutierrez Castanedo G, Menendez Solana G, Fernandez Divar JA, Galindo Rubin P, Alfonso Fernandez A. Hip Chondral Defects: Arthroscopic Treatment With the Needle and Curette Technique and ChondroFiller. Arthroscopy Techniques, 10(7):e1669-e1675, 2021. View DOI
- 2.Meidrix Biomedicals GmbH. ChondroFiller® liquid overview brochure. Manufacturer publication, 2024. View source
- 3.Meidrix Biomedicals GmbH. ChondroFiller® liquid surgical technique. Manufacturer publication, 2022. View source